We have organized and published these 37 papers to present the research origins associated with tiptop and the fields we continue to follow. The bibliography covers lungs and airways, kidneys, the female reproductive tract and endometrium, cell signaling and systems biology, and liver regeneration. Formal titles, publication years, journals and DOIs are retained.

Why retain both research-source and background papers

Thirty papers in the index list Wei Zuo as a coauthor; we classify these as research-source literature. Six are field-background papers, and one Chinese-language review is included as a reference review. This organization shows the research lineage while retaining the academic context needed to understand the questions involved.

Authors and study content follow the original journal records. Cell, tissue, animal and human studies each have their own research subjects.

Five lines of research organize the collection

The 16 papers on lungs and airways connect airway-cell identity, culture, repair and related methods, while retaining respiratory-research and public-health context. Six kidney papers address cell identification, post-injury states, organoids and repair.

Eight papers on the female reproductive tract and endometrium separately retain epithelial-cell research and background literature on endometrial and menstrual-blood-derived cells. Different cell sources and types are presented according to the subjects of the original studies.

Six papers on cell signaling and systems biology cover basic questions involving receptors, signaling regulation, protein interactions and body size. One further paper on liver regeneration records another area of tissue and cell research.

These research sources provide context for our material and translation work. The topical performance of particular products, including CELLshot products, is presented separately through their own finished-product evaluations.

Complete bibliography

Lung and airway regeneration

  1. Autologous transplantation of P63+ lung progenitor cells for chronic obstructive pulmonary disease therapy
    2024 · Sci Transl Med · Research-source literature
    DOI:10.1126/scitranslmed.adi3360

  2. Regeneration of functional alveoli by adult human SOX9+ airway basal cell transplantation
    2018 · Protein Cell · Research-source literature
    DOI:10.1007/s13238-018-0506-y

  3. p63(+)Krt5(+) distal airway stem cells are essential for lung regeneration
    2015 · Nature · Research-source literature
    DOI:10.1038/nature13903

  4. Control of airway basal stem cell-mediated lung repair by TGF-β signaling
    2026 · Sci Adv · Research-source literature
    DOI:10.1126/sciadv.adz1519

  5. Alveolar Differentiation Potency of Human Distal Airway Stem Cells Is Associated with Pulmonary Pathological Conditions
    2019 · Stem Cells Int · Research-source literature
    DOI:10.1155/2019/7123078

  6. Distal airway stem cells ameliorate bleomycin-induced pulmonary fibrosis in mice
    2019 · Stem Cell Res Ther · Research-source literature
    DOI:10.1186/s13287-019-1257-2

  7. Single-Cell RNA Expression Profiling of ACE2, the Receptor of SARS-CoV-2
    2020 · Am J Respir Crit Care Med · Research-source literature
    DOI:10.1164/rccm.202001-0179LE

  8. Genetically engineered distal airway stem cell transplantation protects mice from pulmonary infection
    2020 · EMBO Mol Med · Research-source literature
    DOI:10.15252/emmm.201810233

  9. Single-cell analysis identified lung progenitor cells in COVID-19 patients
    2020 · Cell Prolif · Research-source literature
    DOI:10.1111/cpr.12931

  10. Intrapulmonary distal airway stem cell transplantation repairs lung injury in chronic obstructive pulmonary disease
    2021 · Cell Prolif · Research-source literature
    DOI:10.1111/cpr.13046

  11. Stable Long-Term Culture of Human Distal Airway Stem Cells for Transplantation
    2021 · Stem Cells Int · Research-source literature
    DOI:10.1155/2021/9974635

  12. The Effect of Strict Lockdown on Omicron SARS-CoV-2 Variant Transmission in Shanghai
    2022 · Vaccines (Basel) · Research-source literature
    DOI:10.3390/vaccines10091392

  13. Hypoxic conditions promote a proliferative, poorly differentiated phenotype in COPD lung tissue progenitor cells in vitro
    2023 · Exp Lung Res · Research-source literature
    DOI:10.1080/01902148.2022.2158404

  14. Autologous transplantation of P63+ lung progenitor cells in patients with bronchiectasis: A randomized, single-blind, controlled trial
    2024 · Cell Rep Med · Research-source literature
    DOI:10.1016/j.xcrm.2024.101819

  15. Autologous P63+ lung progenitor cell transplantation in idiopathic pulmonary fibrosis: a phase 1 clinical trial
    2025 · Elife · Research-source literature
    DOI:10.7554/eLife.102451

  16. Cloned airway basal progenitor cells to repair fibrotic lung through re-epithelialization
    2025 · Nat Commun · Research-source literature
    DOI:10.1038/s41467-025-56501-w

Kidney regeneration

  1. Notch-mediated Sox9+ cell activation contributes to kidney repair after partial nephrectomy
    2018 · Life Sci · Research-source literature
    DOI:10.1016/j.lfs.2017.11.041

  2. Single-cell RNA-Seq analysis identified kidney progenitor cells from human urine
    2021 · Protein Cell · Research-source literature
    DOI:10.1007/s13238-020-00816-5

  3. Activated SOX9+ renal epithelial cells promote kidney repair through secreting factors
    2023 · Cell Prolif · Research-source literature
    DOI:10.1111/cpr.13394

  4. Generation of renal tubular organoids from adult SOX9+ kidney progenitor cells
    2023 · Life Med · Research-source literature
    DOI:10.1093/lifemedi/lnad047

  5. Urinary single-cell sequence analysis of the urinary macrophage in different outcomes of membranous nephropathy
    2023 · Clin Kidney J · Research-source literature
    DOI:10.1093/ckj/sfad132

  6. WT1+ glomerular parietal epithelial progenitors promote renal proximal tubule regeneration after severe acute kidney injury
    2023 · Theranostics · Research-source literature
    DOI:10.7150/thno.79326

Female reproductive tract and endometrium

  1. Single-cell transcriptome profiling of the vaginal epithelium reveals the heterogeneity of suprabasal cells
    2023 · Precis Clin Med · Research-source literature
    DOI:10.1093/pcmedi/pbad006

  2. Single-cell analysis defines the lineage plasticity of stem cells in cervix epithelium
    2021 · Cell Regen · Research-source literature
    DOI:10.1186/s13619-021-00096-2

  3. Endometrial Stem/Progenitor Cells-Their Role in Endometrial Repair and Regeneration
    2022 · Front Reprod Health · Field-background literature
    DOI:10.3389/frph.2021.811537

  4. Small extracellular vesicles from menstrual blood-derived mesenchymal stem cells (MenSCs) as a novel therapeutic impetus in regenerative medicine
    2021 · Stem Cell Res Ther · Field-background literature
    DOI:10.1186/s13287-021-02511-6

  5. The multi-functional roles of menstrual blood-derived stem cells in regenerative medicine
    2019 · Stem Cell Res Ther · Field-background literature
    DOI:10.1186/s13287-018-1105-9

  6. Multipotent menstrual blood stromal stem cells: isolation, characterization, and differentiation
    2008 · Cell Transplant · Field-background literature
    DOI:10.3727/096368908784153922

  7. Differentiation of human menstrual blood-derived endometrial mesenchymal stem cells into oocyte-like cells
    2016 · Acta Biochim Biophys Sin (Shanghai) · Field-background literature
    DOI:10.1093/abbs/gmw090

  8. Plasticity of human menstrual blood stem cells derived from the endometrium
    2011 · J Zhejiang Univ Sci B · Field-background literature
    DOI:10.1631/jzus.B1100015

Cell signaling and systems biology

  1. Single-molecule imaging reveals transforming growth factor-beta-induced type II receptor dimerization
    2009 · Proc Natl Acad Sci U S A · Research-source literature
    DOI:10.1073/pnas.0908279106

  2. Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation
    2010 · Nat Cell Biol · Research-source literature
    DOI:10.1038/ncb2082

  3. Monomeric type I and type III transforming growth factor-β receptors and their dimerization revealed by single-molecule imaging
    2010 · Cell Res · Research-source literature
    DOI:10.1038/cr.2010.105

  4. c-Cbl-mediated neddylation antagonizes ubiquitination and degradation of the TGF-β type II receptor
    2013 · Mol Cell · Research-source literature
    DOI:10.1016/j.molcel.2012.12.002

  5. Landscape of protein domain interactome
    2015 · Protein Cell · Research-source literature
    DOI:10.1007/s13238-015-0158-0

  6. 动物体尺寸的控制机理
    2017 · 科学通报(Chinese Science Bulletin) · Reference review
    DOI:10.1360/N972016-01099

Liver regeneration

  1. Clonal expansion of hepatic progenitor cells and differentiation into hepatocyte-like cells
    2019 · Dev Growth Differ · Research-source literature
    DOI:10.1111/dgd.12596