我們整理並公開這37篇文獻,是希望完整交代tiptop相關科研來源及持續關注的研究方向。書目涵蓋肺與氣道、腎臟、女性生殖道與子宮內膜、細胞信號與系統生物學、肝再生,保留正式題名、年份、期刊及DOI。

為什麼把科研來源和背景文獻一併保留

索引中的30篇文獻顯示Wei Zuo參與署名,我們將其列為科研來源相關文獻;6篇列為領域背景文獻;另1篇中文綜述作為參考綜述收錄。這樣的組織方式,既呈現研究來路,也保留理解相關問題所需的學術背景。

各篇作者與研究內容按期刊原文記錄。其中的細胞、組織、動物或人體研究,分別具有自己的研究對象。

我們沿五條線索整理

肺與氣道部分共16篇,連結氣道細胞身份、培養、修復及相關方法,並保留呼吸研究與公共衛生背景。腎臟部分共6篇,圍繞細胞識別、損傷後的狀態、類器官和修復組織資料。

女性生殖道與子宮內膜部分共8篇,我們分別保留上皮細胞研究,以及子宮內膜、月經血來源細胞的背景文獻。不同來源和類型的細胞,在書目中按原研究對象呈現。

細胞信號與系統生物學部分共6篇,覆蓋受體、信號調控、蛋白互作與體尺寸等基礎問題;另有1篇肝再生研究,作為另一類組織與細胞工作的來源記錄。

科研來源為我們的材料與轉化工作提供背景。CELLshot等具體產品的外用表現,則通過相應的成品評價單獨介紹。

完整書目

肺與氣道再生

  1. Autologous transplantation of P63+ lung progenitor cells for chronic obstructive pulmonary disease therapy
    2024 · Sci Transl Med · 科研來源相關文獻
    DOI:10.1126/scitranslmed.adi3360

  2. Regeneration of functional alveoli by adult human SOX9+ airway basal cell transplantation
    2018 · Protein Cell · 科研來源相關文獻
    DOI:10.1007/s13238-018-0506-y

  3. p63(+)Krt5(+) distal airway stem cells are essential for lung regeneration
    2015 · Nature · 科研來源相關文獻
    DOI:10.1038/nature13903

  4. Control of airway basal stem cell-mediated lung repair by TGF-β signaling
    2026 · Sci Adv · 科研來源相關文獻
    DOI:10.1126/sciadv.adz1519

  5. Alveolar Differentiation Potency of Human Distal Airway Stem Cells Is Associated with Pulmonary Pathological Conditions
    2019 · Stem Cells Int · 科研來源相關文獻
    DOI:10.1155/2019/7123078

  6. Distal airway stem cells ameliorate bleomycin-induced pulmonary fibrosis in mice
    2019 · Stem Cell Res Ther · 科研來源相關文獻
    DOI:10.1186/s13287-019-1257-2

  7. Single-Cell RNA Expression Profiling of ACE2, the Receptor of SARS-CoV-2
    2020 · Am J Respir Crit Care Med · 科研來源相關文獻
    DOI:10.1164/rccm.202001-0179LE

  8. Genetically engineered distal airway stem cell transplantation protects mice from pulmonary infection
    2020 · EMBO Mol Med · 科研來源相關文獻
    DOI:10.15252/emmm.201810233

  9. Single-cell analysis identified lung progenitor cells in COVID-19 patients
    2020 · Cell Prolif · 科研來源相關文獻
    DOI:10.1111/cpr.12931

  10. Intrapulmonary distal airway stem cell transplantation repairs lung injury in chronic obstructive pulmonary disease
    2021 · Cell Prolif · 科研來源相關文獻
    DOI:10.1111/cpr.13046

  11. Stable Long-Term Culture of Human Distal Airway Stem Cells for Transplantation
    2021 · Stem Cells Int · 科研來源相關文獻
    DOI:10.1155/2021/9974635

  12. The Effect of Strict Lockdown on Omicron SARS-CoV-2 Variant Transmission in Shanghai
    2022 · Vaccines (Basel) · 科研來源相關文獻
    DOI:10.3390/vaccines10091392

  13. Hypoxic conditions promote a proliferative, poorly differentiated phenotype in COPD lung tissue progenitor cells in vitro
    2023 · Exp Lung Res · 科研來源相關文獻
    DOI:10.1080/01902148.2022.2158404

  14. Autologous transplantation of P63+ lung progenitor cells in patients with bronchiectasis: A randomized, single-blind, controlled trial
    2024 · Cell Rep Med · 科研來源相關文獻
    DOI:10.1016/j.xcrm.2024.101819

  15. Autologous P63+ lung progenitor cell transplantation in idiopathic pulmonary fibrosis: a phase 1 clinical trial
    2025 · Elife · 科研來源相關文獻
    DOI:10.7554/eLife.102451

  16. Cloned airway basal progenitor cells to repair fibrotic lung through re-epithelialization
    2025 · Nat Commun · 科研來源相關文獻
    DOI:10.1038/s41467-025-56501-w

腎臟再生

  1. Notch-mediated Sox9+ cell activation contributes to kidney repair after partial nephrectomy
    2018 · Life Sci · 科研來源相關文獻
    DOI:10.1016/j.lfs.2017.11.041

  2. Single-cell RNA-Seq analysis identified kidney progenitor cells from human urine
    2021 · Protein Cell · 科研來源相關文獻
    DOI:10.1007/s13238-020-00816-5

  3. Activated SOX9+ renal epithelial cells promote kidney repair through secreting factors
    2023 · Cell Prolif · 科研來源相關文獻
    DOI:10.1111/cpr.13394

  4. Generation of renal tubular organoids from adult SOX9+ kidney progenitor cells
    2023 · Life Med · 科研來源相關文獻
    DOI:10.1093/lifemedi/lnad047

  5. Urinary single-cell sequence analysis of the urinary macrophage in different outcomes of membranous nephropathy
    2023 · Clin Kidney J · 科研來源相關文獻
    DOI:10.1093/ckj/sfad132

  6. WT1+ glomerular parietal epithelial progenitors promote renal proximal tubule regeneration after severe acute kidney injury
    2023 · Theranostics · 科研來源相關文獻
    DOI:10.7150/thno.79326

女性生殖道與子宮內膜

  1. Single-cell transcriptome profiling of the vaginal epithelium reveals the heterogeneity of suprabasal cells
    2023 · Precis Clin Med · 科研來源相關文獻
    DOI:10.1093/pcmedi/pbad006

  2. Single-cell analysis defines the lineage plasticity of stem cells in cervix epithelium
    2021 · Cell Regen · 科研來源相關文獻
    DOI:10.1186/s13619-021-00096-2

  3. Endometrial Stem/Progenitor Cells-Their Role in Endometrial Repair and Regeneration
    2022 · Front Reprod Health · 領域背景文獻
    DOI:10.3389/frph.2021.811537

  4. Small extracellular vesicles from menstrual blood-derived mesenchymal stem cells (MenSCs) as a novel therapeutic impetus in regenerative medicine
    2021 · Stem Cell Res Ther · 領域背景文獻
    DOI:10.1186/s13287-021-02511-6

  5. The multi-functional roles of menstrual blood-derived stem cells in regenerative medicine
    2019 · Stem Cell Res Ther · 領域背景文獻
    DOI:10.1186/s13287-018-1105-9

  6. Multipotent menstrual blood stromal stem cells: isolation, characterization, and differentiation
    2008 · Cell Transplant · 領域背景文獻
    DOI:10.3727/096368908784153922

  7. Differentiation of human menstrual blood-derived endometrial mesenchymal stem cells into oocyte-like cells
    2016 · Acta Biochim Biophys Sin (Shanghai) · 領域背景文獻
    DOI:10.1093/abbs/gmw090

  8. Plasticity of human menstrual blood stem cells derived from the endometrium
    2011 · J Zhejiang Univ Sci B · 領域背景文獻
    DOI:10.1631/jzus.B1100015

細胞信號與系統生物學

  1. Single-molecule imaging reveals transforming growth factor-beta-induced type II receptor dimerization
    2009 · Proc Natl Acad Sci U S A · 科研來源相關文獻
    DOI:10.1073/pnas.0908279106

  2. Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation
    2010 · Nat Cell Biol · 科研來源相關文獻
    DOI:10.1038/ncb2082

  3. Monomeric type I and type III transforming growth factor-β receptors and their dimerization revealed by single-molecule imaging
    2010 · Cell Res · 科研來源相關文獻
    DOI:10.1038/cr.2010.105

  4. c-Cbl-mediated neddylation antagonizes ubiquitination and degradation of the TGF-β type II receptor
    2013 · Mol Cell · 科研來源相關文獻
    DOI:10.1016/j.molcel.2012.12.002

  5. Landscape of protein domain interactome
    2015 · Protein Cell · 科研來源相關文獻
    DOI:10.1007/s13238-015-0158-0

  6. 動物體尺寸的控制機理
    2017 · 科學通報(Chinese Science Bulletin) · 參考綜述
    DOI:10.1360/N972016-01099

肝再生

  1. Clonal expansion of hepatic progenitor cells and differentiation into hepatocyte-like cells
    2019 · Dev Growth Differ · 科研來源相關文獻
    DOI:10.1111/dgd.12596